Regeneration Technology
Biomobie Technology
Bioboosti Regeneration Technology

Pulsed electromagnetic field improves postnatal neovascularization in response to hindlimb ischemia

Pulsed electromagnetic field promotes angiogenesis in mice with lower limb ischemia


1.PEMF reduces the incidence of limb necrosis and ischemic ulcer

2.PEMF promotes angiogenesis in the ischemic area

3.PEMF induces the expression of angiogenic factors in vivo

4.PEMF accelerates the proliferation of HUVECs

5.PEMF inhibits apoptosis of HUVECs under serum-free conditions

6.PEMF promotes HUVECs migration and lumen formation

7.PEMF enhances the expression of angiogenic factors in vitro

Pulsed electromagnetic field improves cardiac function in response to myocardial infarction

Pulsed electromagnetic field promotes cardiac function improvement in rats with myocardial infarction


1.PEMF can significantly enhance the function of the left ventricle in rats with acute myocardial infarction without affecting the heart rate of the animals.

2. PEMF significantly increases the number and function of EPC in peripheral blood in rats with acute myocardial infarction.

3.PEMF significantly increases the number of capillaries in myocardial tissue in the dead zone in rats with acute myocardial infarction.

4. PEMF promoted a significant increase in pro-angiogenic factors in the marginal tissue of rats with acute myocardial infarction.

5.PEMF promoted the decrease of apoptotic cardiomyocytes in myocardial tissue in the marginal zone of acute myocardial infarction in rats.

6.PEMF promotes the increase of factors related to angiogenesis, such as VEGF, NO and eNOS, in HUVEC cell culture supernatant.

Novel protective effects of pulsed electromagnetic field ischemia/reperfusion injury rats

Effect of pulsed electromagnetic field on ischemia/reperfusion injury in rats


1.PEMF can reduce blood pressure in rats with essential hypertension (double-blind test).

2.PEMF promotes a significant increase in the number and function of EPC.

3.PEMF can significantly protect the myocardium from myocardial infarction/ischemia in rats with perfusion injury.

4.PEMF significantly reduces apoptosis caused by I/R.

5.PEMF promotes the increase of NO content.
Biomobie Corp., USA
Biomobie (Shanghai) Regenerative Medicine co., Ltd.

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